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La Jolla Pharmaceutical Company
La Jolla Pharmaceutical Company
(LJPC)
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Drug Name
Phase 1
Phase 2
Phase 3
Phase 4
Indication
Angiotensin ii
peripheral arterial disease
,
peripheral vascular diseases
,
infections
,
fibrosis
,
hiv infections
,
acquired immunodeficiency syndrome
,
communicable diseases
,
type 1 diabetes mellitus
,
polycystic kidney diseases
,
essential hypertension
,
marfan syndrome
,
pathologic dilatation
,
syndrome
,
arachnodactyly
,
hypertension
,
kidney diseases
,
chronic obstructive pulmonary disease
,
emphysema
,
chronic bronchitis
,
bronchitis
,
pulmonary emphysema
,
smoking
,
obesity
,
insulin resistance
,
hyperglycemia
,
proteinuria
Ademetionine
lymphoma
,
myeloid leukemia chronic-phase
,
myeloid leukemia
,
leukemia
,
bcr-abl positive chronic myelogenous leukemia
,
pancreatic neoplasms
,
carcinoma
,
vitiligo
,
b-cell lymphoma
,
glioblastoma
,
glioma
,
precursor cell lymphoblastic leukemia-lymphoma
,
lymphoid leukemia
,
colorectal neoplasms
,
breast neoplasms
,
lung neoplasms
,
squamous cell carcinoma of head and neck
,
squamous cell carcinoma
,
neoplasms
,
hidradenitis suppurativa
,
hidradenitis
,
lichen sclerosus et atrophicus
,
lichen planus
,
adenosquamous carcinoma
,
asthma
,
cholangiocarcinoma
,
polycythemia vera
,
myeloproliferative disorders
,
primary myelofibrosis
,
polycythemia
Calcium dobesilate
multiple myeloma
,
plasma cell neoplasms
,
lymphoma
,
large b-cell lymphoma diffuse
,
b-cell lymphoma
Serine
healthy volunteers/patients
,
liver diseases
,
hepatic insufficiency
,
renal insufficiency
,
coronary disease
,
balloon angioplasty coronary
,
emphysema
,
alpha 1-antitrypsin deficiency
,
pulmonary emphysema
,
thrombosis
,
venous thrombosis
,
thromboembolism
,
pulmonary embolism
,
embolism
,
homozygous familial hypercholesterolemia
,
atrial fibrillation
,
hemophilia a
,
unstable angina
,
sepsis
,
septic shock
,
shock
,
cardiovascular diseases
,
atherosclerosis
,
hypercholesterolemia
,
hyperlipoproteinemia type ii
,
acute coronary syndrome
,
myocardial infarction
,
infarction
,
coronary artery disease
,
myocardial ischemia
,
syndrome
,
atherosclerotic plaque
,
dyslipidemias
Sodium chloride
fabry disease
Sodium lactate
pain
,
interstitial cystitis
,
syndrome
,
cystitis
,
inflammation
,
infections
,
communicable diseases
,
eye infections
,
atrophy
,
vaginitis
,
atrophic vaginitis
,
bacterial vaginosis
,
vaginal diseases
,
pruritus vulvae
,
vaginal discharge
,
acne vulgaris
,
keratoconjunctivitis sicca
,
dry eye syndromes
,
eye diseases
Aldosterone
heart failure
,
hyperkalemia
,
chronic renal insufficiency
,
hypertension
,
kidney diseases
,
left ventricular dysfunction
,
systolic murmurs
Aspartame
prostatic hyperplasia
,
hyperplasia
,
healthy volunteers/patients
,
respiratory tract diseases
,
respiration disorders
,
hyperhidrosis
,
kidney diseases
,
obesity
,
weight loss
,
burns
,
bronchiectasis
,
respiratory tract infections
,
skin diseases
,
premature obstetric labor
,
heart failure
,
pulmonary edema
,
amyloidosis
,
bacterial infections
,
liver diseases
,
hepatic insufficiency
,
sepsis
,
neoplasms
,
multiple myeloma
,
plasma cell neoplasms
,
common cold
,
breast neoplasms
,
rhinitis
,
tuberculosis
,
atherosclerosis
,
obstructive lung diseases
,
virus diseases
,
pancreatic neoplasms
,
lymphoma
,
follicular lymphoma
,
allergic rhinitis
,
pulmonary tuberculosis
,
coronary disease
,
coronary artery disease
,
myocardial ischemia
,
heart diseases
,
carcinoma
,
hepatocellular carcinoma
,
liver neoplasms
,
precursor cell lymphoblastic leukemia-lymphoma
,
precursor t-cell lymphoblastic leukemia-lymphoma
,
sjogren's syndrome
,
xerostomia
,
ulcer
,
buruli ulcer
,
hiv infections
,
malaria
,
systemic lupus erythematosus
,
infections
,
acquired immunodeficiency syndrome
,
vivax malaria
,
type 2 diabetes mellitus
,
human influenza
,
communicable diseases
,
hemolysis
,
neoplasm metastasis
,
bone fractures
,
parkinson disease
,
pemphigus
,
migraine disorders
,
depression
,
major depressive disorder
,
depressive disorder
,
churg-strauss syndrome
,
granulomatosis with polyangiitis
,
systemic vasculitis
,
eosinophilic granuloma
,
neisseria meningitidis
,
haemophilus influenzae type b
,
restless legs syndrome
,
psychomotor agitation
,
syndrome
,
covid-19
,
arthralgia
,
recurrence
,
ovarian neoplasms
,
anthrax
,
asthma
,
chronic obstructive pulmonary disease
,
lung diseases
,
diabetes mellitus
,
hepatitis
,
hepatitis a
,
nausea
,
pulmonary eosinophilia
,
prostatic neoplasms
,
growth and development
,
neuralgia
,
herpes zoster
,
postherpetic neuralgia
,
herpes simplex
Bevifimod
renal cell carcinoma
,
human influenza
,
nutritional status
,
pneumococcal infections
,
pneumococcal pneumonia
,
leishmaniasis
,
psoriasis
,
systemic lupus erythematosus
,
cutaneous lupus erythematosus
,
inflammatory bowel diseases
,
virus diseases
,
urticaria
,
tendon injuries
,
dermatitis
,
haemophilus influenzae
,
streptococcus pneumoniae
,
cancer pain
,
oncogenes
,
crohn disease
,
energy metabolism
,
endometrial neoplasms
,
carcinosarcoma
,
mullerian mixed tumor
,
fibrosis
,
idiopathic pulmonary fibrosis
,
pulmonary fibrosis
,
lung neoplasms
,
non-small-cell lung carcinoma
,
malaria
,
neoplasm metastasis
,
carcinoma
,
falciparum malaria
,
ovarian neoplasms
,
brain neoplasms
,
healthy volunteers/patients
,
prostatic neoplasms
,
asthma
,
recurrence
,
colorectal neoplasms
,
squamous cell carcinoma
,
multiple myeloma
,
plasma cell neoplasms
,
ovarian epithelial carcinoma
,
cutaneous malignant melanoma
,
skin neoplasms
,
type 1 diabetes mellitus
,
triple negative breast neoplasms
,
squamous cell carcinoma of head and neck
,
sickle cell anemia
,
myeloid leukemia acute
,
myeloid leukemia
,
leukemia
,
hepatitis b
,
chronic hepatitis b
,
hepatitis
,
primary myelofibrosis
,
hepatocellular carcinoma
,
liver neoplasms
,
fallopian tube neoplasms
,
pancreatic neoplasms
,
neuralgia
,
hematologic neoplasms
,
ductal carcinoma
,
circulating neoplastic cells
,
uterine neoplasms
,
uterine cervical neoplasms
,
glioma
,
streptococcus agalactiae
,
lymphoma
,
follicular lymphoma
,
neisseria meningitidis
,
haemophilus influenzae type b
,
invasive hydatidiform mole
,
biliary tract neoplasms
,
uveal neoplasms
,
respiratory tract diseases
,
respiration disorders
,
proteinuria
,
focal segmental glomerulosclerosis
,
cytomegalovirus infections
,
chronic hepatitis
,
kidney diseases
,
membranous glomerulonephritis
,
nephrotic syndrome
,
nephrosis
,
glioblastoma
,
endometrioid carcinoma
,
breast diseases
,
squamous cell neoplasms
,
neurofibromatosis 2
,
acoustic neuroma
,
neurofibromatosis 1
,
neurofibromatoses
,
neurofibroma
,
neurilemmoma
,
drug therapy
,
tuberculosis
,
pulmonary tuberculosis
,
adenocarcinoma of lung
,
disease progression
,
peritoneal neoplasms
,
inflammation
,
beta-thalassemia
,
thalassemia
,
sickle cell trait
,
essential thrombocythemia
,
polycythemia vera
,
thrombocytosis
,
polycythemia
,
ulcer
,
buruli ulcer
,
breast neoplasms
,
melanoma
,
rheumatoid arthritis
,
arthritis
,
head and neck neoplasms
,
inflammatory breast neoplasms
,
adenocarcinoma
,
respiratory syncytial virus infections
,
covid-19
,
bacterial infections
,
cellulitis
,
streptococcal infections
,
hepatitis a
,
stomach neoplasms
,
gastrointestinal neoplasms
,
digestive system neoplasms
,
infectious skin diseases
,
bacterial skin diseases
,
ductal carcinoma breast
,
renal insufficiency
,
mumps
,
measles
,
rubella
,
urinary bladder neoplasms
,
acute coronary syndrome
,
syndrome
,
rotavirus infections
,
otitis media
,
mucinous adenocarcinoma
,
meningitis
,
meningococcal meningitis
,
impetigo
,
respiratory syncytial viruses
,
herpes zoster
,
neoplasms
,
type 2 diabetes mellitus
,
diabetes mellitus
,
hiv infections
,
infections
,
acquired immunodeficiency syndrome
,
acne vulgaris
,
chronic obstructive pulmonary disease
,
communicable diseases
,
lung diseases
,
obstructive lung diseases
,
pneumonia
,
dental focal infection
,
focal infection
,
nausea
,
hiv
,
immunologic deficiency syndromes
,
ventilator-associated pneumonia
,
growth and development
,
immunologic tests
,
cognition
,
alzheimer disease
,
wasting syndrome
,
cachexia
,
dyslipidemias
,
insulin resistance
,
abdominal obesity
,
lipid metabolism
,
latent autoimmune diabetes in adults
,
community-acquired infections
,
abscess
,
folliculitis
,
staphylococcal infections
,
resistance training
,
exercise
,
depression
,
major depressive disorder
,
depressive disorder
,
thyroid neoplasms
,
papillary thyroid cancer
,
thyroid diseases
,
clostridioides difficile
Hepcidin
inflammation
,
healthy volunteers/patients
,
iron overload
,
chronic disease
,
thalassemia
,
hemochromatosis
,
hemosiderosis
,
beta-thalassemia
,
ovarian neoplasms
,
disease
,
diagnosis
,
ovarian epithelial carcinoma
,
dysbiosis
,
chronic renal insufficiency
,
kidney diseases
,
polycythemia vera
,
polycythemia
,
critical care
,
essential thrombocythemia
,
primary myelofibrosis
,
thrombocytosis
,
postoperative hemorrhage
,
anemia
,
iron deficiencies
,
iron-deficiency anemia
,
metabolic diseases
,
chronic kidney failure
,
vitamin d deficiency
,
colorectal neoplasms
,
inflammatory bowel diseases
,
periodontitis
,
deficiency diseases
,
renal insufficiency
,
metabolic bone diseases
,
bone diseases
,
crohn disease
,
chronic periodontitis
,
neoplasm metastasis
,
iron metabolism disorders
,
obesity
,
sepsis
,
sickle cell anemia
,
hepatitis c
,
hepatitis
,
hepatitis a
,
fibrosis
,
cystic fibrosis
,
type 2 diabetes mellitus
,
overweight
,
septic shock
,
toxemia
,
hemolysis
,
hemolytic anemia
,
hypertension
,
pulmonary arterial hypertension
,
familial primary pulmonary hypertension
,
critical illness
,
pulmonary fibrosis
,
heart failure
,
infections
,
hemoglobinopathies
,
glucose intolerance
,
gestational diabetes
,
diabetes mellitus
,
metabolic syndrome
,
syndrome
,
intraoperative complications
,
systemic inflammatory response syndrome
,
heart diseases
,
heart valve diseases
,
pregnancy
,
periodontal diseases
,
gaucher disease
,
oxidative stress
,
mycoses
,
bacterial infections
,
bacterial infections and mycoses
,
premature birth
,
neonatal sepsis
,
cardiac surgical procedures
,
coronary artery disease
,
shock
,
myositis
,
metabolic brain diseases
,
weight loss
,
endometrial neoplasms
,
fallopian tube neoplasms
,
female genital neoplasms
,
male breast neoplasms
Microcrystalline cellulose
pain
,
interstitial cystitis
,
syndrome
,
cystitis
,
inflammation
,
infections
,
communicable diseases
,
eye infections
,
atrophy
,
vaginitis
,
atrophic vaginitis
,
bacterial vaginosis
,
vaginal diseases
,
pruritus vulvae
,
vaginal discharge
,
acne vulgaris
,
keratoconjunctivitis sicca
,
dry eye syndromes
,
eye diseases
Vp16
leukemia
,
precursor cell lymphoblastic leukemia-lymphoma
,
philadelphia chromosome
,
lymphoid leukemia
,
multiple myeloma
,
plasma cell neoplasms
,
plasmacytoma
,
lymphoma
,
sarcoma
,
hiv infections
,
kaposi sarcoma
,
non-hodgkin lymphoma
,
large b-cell lymphoma diffuse
,
b-cell lymphoma
,
aggression
,
t-cell lymphoma
,
t-cell lymphoma peripheral
,
carcinoma
,
neuroendocrine carcinoma
,
prostatic neoplasms
,
small cell lung carcinoma
,
lung neoplasms
,
non-small-cell lung carcinoma
Catecholamines
healthy volunteers/patients
,
endocrine system diseases
,
exercise
,
psychotic disorders
,
pheochromocytoma
,
myocardial infarction
,
hyperkinesis
,
schizophrenia
,
neuroendocrine tumors
,
paraganglioma
,
infarction
,
inferior wall myocardial infarction
,
narcolepsy
,
neuroendocrine carcinoma
,
sleep initiation and maintenance disorders
,
craniocerebral trauma
,
nervous system trauma
,
drug-related side effects and adverse reactions
,
temporomandibular joint disorders
,
temporomandibular joint dysfunction syndrome
,
traumatic stress disorders
,
traumatic stress disorders acute
,
autonomic nervous system diseases
,
hypotension
,
nervous system diseases
,
primary dysautonomias
,
obesity
,
syndrome
,
orthostatic intolerance
,
postural orthostatic tachycardia syndrome
,
anorexia
,
orthostatic hypotension
,
cardiac surgical procedures
,
respiratory distress syndrome
,
bronchiolitis
,
weight loss
,
fluid therapy
,
infections
,
low cardiac output
,
cachexia
,
acute lung injury
,
newborn respiratory distress syndrome
,
carotid stenosis
,
neonatal sepsis
,
shock
,
septic shock
,
hypertension
,
wounds and injuries
,
sepsis
,
diabetes mellitus
,
hypoglycemia
,
traumatic brain injuries
,
brain injuries
,
heart failure
,
type 1 diabetes mellitus
,
tachycardia
,
critical illness
,
cardiogenic shock
,
type 2 diabetes mellitus
,
cardiac arrhythmias
,
covid-19
,
coronavirus infections
,
respiratory tract diseases
,
respiration disorders
,
endotoxemia
,
parkinson disease
,
psychological stress
,
acute kidney injury
,
pure autonomic failure
,
inflammation
,
depressive disorder
,
respiratory insufficiency
,
cardiovascular diseases
,
takotsubo cardiomyopathy
,
essential hypertension
,
depression
,
attention deficit disorder with hyperactivity
,
heart arrest
,
cardiomyopathies
,
hemorrhage
,
ischemic stroke
,
subarachnoid hemorrhage
,
stroke
,
adrenal gland neoplasms
,
adrenocortical carcinoma
,
anorexia nervosa
,
hyperaldosteronism
,
chronic kidney failure
,
bradycardia
,
shy-drager syndrome
,
multiple system atrophy
,
atrophy
,
autoimmune diseases
,
major depressive disorder
,
bulimia
,
feeding and eating disorders
,
bulimia nervosa
,
reward
,
kidney diseases
,
heart diseases
,
metabolic syndrome
,
neuralgia
,
restless legs syndrome
,
psychomotor agitation
,
physiological stress
,
burns
,
intraoperative complications
,
high cardiac output
,
respiratory aspiration of gastric contents
,
multiple organ failure
,
hyperemia
,
adrenal insufficiency
,
prostatic neoplasms
,
chronic obstructive pulmonary disease
,
treatment outcome
,
cytokine release syndrome
,
toxemia
,
mammaplasty
,
free tissue flaps
,
microsurgery
,
glaucoma
,
raynaud disease
,
hand-arm vibration syndrome
,
postoperative pain
,
postoperative complications
,
ultrasonic therapy
,
vitiligo
,
hematoma
,
pulmonary embolism
,
embolism
,
obstructive sleep apnea
,
sleep apnea syndromes
,
apnea
,
menopause
,
sudden death cardiac
,
death
,
food intolerance
,
enteral nutrition
,
vasovagal syncope
,
syncope
,
post-traumatic stress disorders
,
abdominal obesity
,
adrenocortical adenoma
,
delirium
,
melanoma
,
acute coronary syndrome
,
pancreatitis
,
phenylketonurias
,
aphthous stomatitis
,
stomatitis
,
thyroid diseases
,
neuroblastoma
,
precancerous conditions
,
hyperplasia
,
congenital adrenal hyperplasia
,
adrenogenital syndrome
,
adrenocortical hyperfunction
,
open-angle glaucoma
,
hypersensitivity
,
laparoscopic cholecystectomy
,
lung injury
,
heart disease risk factors
,
sleep
,
circadian rhythm
,
knee osteoarthritis
,
osteoarthritis
,
fasting
,
cold temperature
,
myofascial pain syndromes
,
fibromyalgia
,
renal insufficiency
,
hypoxia
,
altitude sickness
,
resistance training
,
blood flow restriction therapy
,
pituitary acth hypersecretion
,
cushing syndrome
,
adrenal rest tumor
,
adrenal gland diseases
,
neoplasm metastasis
,
spinal cord injuries
,
pulmonary heart disease
,
extracorporeal membrane oxygenation
,
hypothermia
,
out-of-hospital cardiac arrest
,
post-cardiac arrest syndrome
,
temperature
Mydfrin
dental anesthesia
,
anesthesia
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